HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 67782192, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-{[(3-Methylphenyl)carbamoyl]amino}acetic acid | HCID 14996960 | — |
| Reactant | HCID 54412221 | HCID 54412221 | — |
| Product | HCID 67782192 | HCID 67782192 | 16.1% |
Reaction Steps
Using a procedure similar to that described in Example 17, but starting with 2-[(3-methylphenyl)ureido]acetic acid (2.08 g), tert-butyl 2-[(3-trifluoromethylthiophenyl)amino]acetate (3.07 g) and sulphinyl chloride (1.3 g), and after recrystallisation in diisopropyl ether, tert-butyl 2-{2-[3-(3-methylphenyl)ureido]-N-(3-trifluoromethylthiophenyl)acetamido}acetate (0.8 g), m.p. 112° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05475106 |
| Source dataset | uspto-grants-1995_12 |
| ORD ID | ord-41151656db1842059c9bde002d057d18 |
| Source note | uspto-grants-1995_12 |