m-Tolyl isocyanate → HCID 15670988, compound

Participants

Reaction Steps

Using a procedure similar to that described in Example 27, but starting with tert-butyl 2-{2-amino-N-[2-(1,2,3,4-tetrahydro-1-quinolyl)carbonylphenyl]acetamido}acetate (2 g) and 3-methylphenyl isocyanate (0.63 g), and after recrysallisation in ethyl acetate, tert-butyl 2-{2-[3-(3-methylphenyl)ureido]-N-[2-(1,2,3,4-tetrahydro-1-quinolyl)carbonylphenyl]acetamido}acetate (1.2 g), m.p. 160° C., is obtained.

Provenance & Evidence