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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 226003Generated: October 29, 2026

HCID 68827261, compound → HCID 68828779, compound

https://huagongshe.com/reaction/226003

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68827261HCID 68827261—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 68828779HCID 6882877959.8%

Reaction Steps

A solution of 4-Allyl-3-[7-(4-ethoxy-phenylamino)-6-methyl-pyrazolo[1,5-a]pyrimidin-5-ylamino]-piperidine-1-carboxylic acid benzyl ester (3.1 mg) in EtOH (1.5 mL) was hydrogenated in the presence of 10% palladium on carbon (7.5 mg) for 45 min. The mixture was filtered through a pad of Celite and evapotrated. The residue was purified on preparative TLC to give the title compound (1.4 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557110B2
Source datasetuspto-grants-2009_07
ORD IDord-9eb1cdd6563e4dbd8460debcbd5fb103
Source noteuspto-grants-2009_07