HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68827261, compound → HCID 68828779, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68827261 | HCID 68827261 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68828779 | HCID 68828779 | 59.8% |
Reaction Steps
A solution of 4-Allyl-3-[7-(4-ethoxy-phenylamino)-6-methyl-pyrazolo[1,5-a]pyrimidin-5-ylamino]-piperidine-1-carboxylic acid benzyl ester (3.1 mg) in EtOH (1.5 mL) was hydrogenated in the presence of 10% palladium on carbon (7.5 mg) for 45 min. The mixture was filtered through a pad of Celite and evapotrated. The residue was purified on preparative TLC to give the title compound (1.4 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557110B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-9eb1cdd6563e4dbd8460debcbd5fb103 |
| Source note | uspto-grants-2009_07 |