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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2260039Generated: October 29, 2026

m-Fluorotoluene → 2,4-Dichloro-5-fluorotoluene

https://huagongshe.com/reaction/2260039

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-FluorotolueneHCID 9606—
Reactant2-Chloro-5-fluorotolueneHCID 118475—
Reactant4-Chloro-3-fluorotolueneHCID 2736590—
ReactantHCID 11830014HCID 11830014—
Product2,4-Dichloro-5-fluorotolueneHCID 2758114—

Reaction Steps

3-Fluoro-4,6-dichlorotoluene is prepared with reduced formation of 3-fluoro-2,6-dichlorotoluene by chlorinating 3-fluorotoluene in the presence of a catalyst system to give a mixture containing 3-fluoro-6-chlorotoluene and 3-fluoro-4-chlorotoluene and chlorinating this in the presence of another catalyst system to give 3-fluoro-4,6-dichlorotoluene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05475164
Source datasetuspto-grants-1995_12
ORD IDord-2cb82142fc9d48358ae049a96f189f35
Source noteuspto-grants-1995_12