HCID 10508355, compound → HCID 178439940, compound

HRID 2260044Notes

Reaction equation

HRID 2260044 reaction equation
[CH3:1][C:2]1[N:3]([CH2:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[C:26]3[N:30](C(C4C=CC=CC=4)(C4C=CC=CC=4)C4C=CC=CC=4)[N:29]=[N:28][N:27]=3)=[CH:16][CH:15]=2)[N:4]2[C:8]([CH:9]=1)=[N:7][C:6]([CH2:10][CH2:11][CH3:12])=[N:5]2.CC1C=C2N(N=C(CCC)N2)N=1>>[CH3:1][C:2]1[N:3]([CH2:13][C:14]2[CH:15]=[CH:16][C:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[C:26]3[NH:30][N:29]=[N:28][N:27]=3)=[CH:18][CH:19]=2)[N:4]2[C:8]([CH:9]=1)=[N:7][C:6]([CH2:10][CH2:11][CH3:12])=[N:5]2

Participants

3

Reactant 2

HCID 10508355HCID 10508355, compound2×HCID 178440295HCID 178440295, compound

Product 1

HCID 178439940HCID 178439940, compound

Procedure

A 359 mg portion of the mixed product obtained in Example 6 consisting (about 2:1) of 6-methyl-2-propyl-5-[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-5H-pyrazolo[1,5-b][1,2,4]triazole (compound 6c) and 6-methyl-2-propyl-1H-pyrazolo[1,5-b][1,2,4]triazole was treated in the same manner as described in Example 23 to give 126 mg of 6-methyl-2-propyl-5-[[2'-(tetrazol-5-yl)biphenyl-4-yl]methyl]-5H-pyrazolo[1,5-b][1,2,4]triazole in the form of colorless crystals.

Sources & evidence

ORD record
ord-61a2e3bffc6c4496b756daf4752a8d0a
Source dataset
uspto-grants-1995_12
Patent number
US05475114

Reaction notes

Loading…