HCID 10508204, compound → HCID 19002121, compound

HRID 2260049Notes

Reaction equation

HRID 2260049 reaction equation
[CH2:1]([C:3]1[N:4]=[C:5]2[C:10]([CH3:11])=[CH:9][N:8](CC3C=CC(C4C=CC=CC=4C4N(C(C5C=CC=CC=5)(C5C=CC=CC=5)C5C=CC=CC=5)N=NN=4)=CC=3)[N:6]2[N:7]=1)[CH3:2].[CH2:49]([C:51]1[N:52]([CH2:60][C:61]2[CH:66]=[CH:65][C:64]([C:67]3[CH:72]=[CH:71][CH:70]=[CH:69][C:68]=3[C:73]3[N:77]([C:78]([C:91]4[CH:96]=[CH:95][CH:94]=[CH:93][CH:92]=4)([C:85]4[CH:90]=[CH:89][CH:88]=[CH:87][CH:86]=4)[C:79]4[CH:84]=[CH:83][CH:82]=[CH:81][CH:80]=4)[N:76]=[N:75][N:74]=3)=[CH:63][CH:62]=2)[C:53]2[N:54]([N:56]=[CH:57][C:58]=2[CH3:59])[N:55]=1)[CH3:50]>>[CH2:49]([C:51]1[N:52]([CH2:60][C:61]2[CH:62]=[CH:63][C:64]([C:67]3[CH:72]=[CH:71][CH:70]=[CH:69][C:68]=3[C:73]3[N:77]([C:78]([C:79]4[CH:84]=[CH:83][CH:82]=[CH:81][CH:80]=4)([C:91]4[CH:92]=[CH:93][CH:94]=[CH:95][CH:96]=4)[C:85]4[CH:86]=[CH:87][CH:88]=[CH:89][CH:90]=4)[N:76]=[N:75][N:74]=3)=[CH:65][CH:66]=2)[C:53]2[N:54]([N:56]=[CH:57][C:58]=2[CH3:59])[N:55]=1)[CH3:50].[CH2:1]([C:3]1[NH:4][C:5]2[N:6]([N:8]=[CH:9][C:10]=2[CH3:11])[N:7]=1)[CH3:2]

Participants

4

Reactant 2

HCID 10508204HCID 10508204, compound2×HCID 19002121HCID 19002121, compound

Product 2

HCID 19002121HCID 19002121, compoundHCID 178437909HCID 178437909, compound

Procedure

In the same manner as described in Example 38, 1.5 g of 2-ethyl-7-methyl-5-[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-5H-pyrazolo[1,5-b][1,2,4]triazole (compound 44a) and 330 mg of 2-ethyl-7-methyl-1-[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-pyrazolo[1,5-b][1,2,4]triazole (compound 44b) were obtained from 500 mg of 2-ethyl-7-methyl-1H-pyrazolo[1,5-b][1,2,4]triazole.

Sources & evidence

ORD record
ord-58d0469077dc4b719d47d89761b3872f
Source dataset
uspto-grants-1995_12
Patent number
US05475114

Reaction notes

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