HCID 19002170, compound → HCID 178440589, compound

HRID 2260054Notes

Reaction equation

HRID 2260054 reaction equation
[C:1]1([C:7]([C:83]2[CH:88]=[CH:87][CH:86]=[CH:85][CH:84]=2)([C:77]2[CH:82]=[CH:81][CH:80]=[CH:79][CH:78]=2)[N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[C:19]3[CH:24]=[CH:23][C:22]([CH2:25][N:26]4[N:30]5[N:31]=[C:32]([CH2:34][CH3:35])[N:33]=[C:29]5[C:28](CC5C=CC(C6C=CC=CC=6C6N(C(C7C=CC=CC=7)(C7C=CC=CC=7)C7C=CC=CC=7)N=NN=6)=CC=5)=[C:27]4[CH2:73][CH2:74][CH2:75][CH3:76])=[CH:21][CH:20]=3)=[N:11][N:10]=[N:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:89]([C:93]1[CH:100]=[C:99]2[N:95]([N:96]=[C:97]([CH2:138][CH3:139])[N:98]2CC2C=CC(C3C=CC=CC=3C3N(C(C4C=CC=CC=4)(C4C=CC=CC=4)C4C=CC=CC=4)N=NN=3)=CC=2)[N:94]=1)[CH2:90][CH2:91][CH3:92].C(C1C(CC2C=CC(C3C=CC=CC=3C3N(C(C4C=CC=CC=4)(C4C=CC=CC=4)C4C=CC=CC=4)N=NN=3)=CC=2)=C2N(N=C(CC)N2)N=1)CCC>>[CH2:73]([C:27]1[N:26]([CH2:25][C:22]2[CH:21]=[CH:20][C:19]([C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=3[C:12]3[N:8]([C:7]([C:77]4[CH:78]=[CH:79][CH:80]=[CH:81][CH:82]=4)([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)[C:83]4[CH:84]=[CH:85][CH:86]=[CH:87][CH:88]=4)[N:9]=[N:10][N:11]=3)=[CH:24][CH:23]=2)[N:30]2[C:29]([CH:28]=1)=[N:33][C:32]([CH2:34][CH3:35])=[N:31]2)[CH2:74][CH2:75][CH3:76].[CH2:89]([C:93]1[CH:100]=[C:99]2[N:95]([N:96]=[C:97]([CH2:138][CH3:139])[NH:98]2)[N:94]=1)[CH2:90][CH2:91][CH3:92]

Participants

5

Reactant 3

HCID 19002170HCID 19002170, compound2×HCID 19002250HCID 19002250, compound2×HCID 178441899HCID 178441899, compound2×

Product 2

HCID 10699631HCID 10699631, compoundHCID 178440589HCID 178440589, compoundYield 2,285.4%

Procedure

In the same manner as described in Example 38, 0.61 g of 5,7-bis[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-6-butyl-2-ethyl-5H-pyrazolo[1,5-b][1,2,4]triazole (compound 50a), 2.52 g of 6-butyl-2-ethyl-1-[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-pyrazolo[1,5-b][1,2,4]triazole (compound 50b), and 2.31 g of a mixture consisting (about 1:8) of 6-butyl-2-ethyl-7-[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-pyrazolo[1,5-b][1,2,4]triazole (compound 50c) and 6-butyl-2-ethyl-5-[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-5H-pyrazolo[1,5-b][1,2,4]triazole (compound 50d) were obtained from 2.34 g of 6-butyl-2-ethyl-1H-pyrazolo[1,5-b][1,2,4]triazole.

Sources & evidence

ORD record
ord-9b2d285f18cc442d898364d14d509778
Source dataset
uspto-grants-1995_12
Patent number
US05475114

Reaction notes

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