HCID 53802068, compound → HCID 54063000, compound
Reaction equation
[CH2:1]([C:3]1[CH:4]=[N:5][N:6]2[C:10]=1[N:9](CC1C=CC(C3C=CC=CC=3C3N(C(C4C=CC=CC=4)(C4C=CC=CC=4)C4C=CC=CC=4)N=NN=3)=CC=1)[C:8]([CH2:48][C:49]([O:51][CH2:52][CH3:53])=[O:50])=[N:7]2)[CH3:2].[CH2:54]([C:56]1[C:63]2[N:59]([N:60]=[C:61]([CH2:64][C:65]([O:67][CH2:68][CH3:69])=[O:66])[N:62]=2)[N:58]([CH2:70][C:71]2[CH:76]=[CH:75][C:74]([C:77]3[CH:82]=[CH:81][CH:80]=[CH:79][C:78]=3[C:83]3[N:87]([C:88]([C:101]4[CH:106]=[CH:105][CH:104]=[CH:103][CH:102]=4)([C:95]4[CH:100]=[CH:99][CH:98]=[CH:97][CH:96]=4)[C:89]4[CH:94]=[CH:93][CH:92]=[CH:91][CH:90]=4)[N:86]=[N:85][N:84]=3)=[CH:73][CH:72]=2)[CH:57]=1)[CH3:55]>>[CH2:54]([C:56]1[C:63]2[N:59]([N:60]=[C:61]([CH2:64][C:65]([O:67][CH2:68][CH3:69])=[O:66])[N:62]=2)[N:58]([CH2:70][C:71]2[CH:72]=[CH:73][C:74]([C:77]3[CH:82]=[CH:81][CH:80]=[CH:79][C:78]=3[C:83]3[N:87]([C:88]([C:89]4[CH:94]=[CH:93][CH:92]=[CH:91][CH:90]=4)([C:101]4[CH:102]=[CH:103][CH:104]=[CH:105][CH:106]=4)[C:95]4[CH:96]=[CH:97][CH:98]=[CH:99][CH:100]=4)[N:86]=[N:85][N:84]=3)=[CH:75][CH:76]=2)[CH:57]=1)[CH3:55].[CH2:1]([C:3]1[CH:4]=[N:5][N:6]2[C:10]=1[NH:9][C:8]([CH2:48][C:49]([O:51][CH2:52][CH3:53])=[O:50])=[N:7]2)[CH3:2]Participants
4
Procedure
In the same manner as described in Example 66, 0.12 g of ethyl [7-ethyl-1-[[2'-(N-triphenylmethyl-tetrazol- 5-yl)biphenyl-4-yl]methyl]-1H-pyrazolo[1,5-b][1,2,4]triazol-2-yl]acetate (compound 76a) and 1.11 g of ethyl [7-ethyl-5-[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-5H-pyrazolo[1,5-b][1,2,4]triazol-2-yl]acetate (compound 76b) were obtained from 0.53 g of ethyl [7-ethyl-1H-pyrazolo[1,5-b][1,2,4]triazol-2-yl]acetate.
Sources & evidence
- ORD record
- ord-3f3795c0b2c042b9be636f22d8cf70e4
- Source dataset
- uspto-grants-1995_12
- Patent number
- US05475114
Reaction notes
Loading…