HCID 10532613, compound → HCID 10532613, compound

HRID 2260061Notes

Reaction equation

HRID 2260061 reaction equation
[CH2:1]([C:3]1[N:4](CC2C=CC(C3C=CC=CC=3C3N(C(C4C=CC=CC=4)(C4C=CC=CC=4)C4C=CC=CC=4)N=NN=3)=CC=2)[C:5]2[N:6]([N:8]=[C:9]([CH2:13][O:14][CH3:15])[C:10]=2[CH2:11][CH3:12])[N:7]=1)[CH3:2].[CH2:53]([C:55]1[N:56]=[C:57]2[C:62]([CH2:63][CH3:64])=[C:61]([CH2:65][O:66][CH3:67])[N:60]([CH2:68][C:69]3[CH:74]=[CH:73][C:72]([C:75]4[CH:80]=[CH:79][CH:78]=[CH:77][C:76]=4[C:81]4[N:85]([C:86]([C:99]5[CH:104]=[CH:103][CH:102]=[CH:101][CH:100]=5)([C:93]5[CH:98]=[CH:97][CH:96]=[CH:95][CH:94]=5)[C:87]5[CH:92]=[CH:91][CH:90]=[CH:89][CH:88]=5)[N:84]=[N:83][N:82]=4)=[CH:71][CH:70]=3)[N:58]2[N:59]=1)[CH3:54]>>[CH2:53]([C:55]1[N:56]=[C:57]2[C:62]([CH2:63][CH3:64])=[C:61]([CH2:65][O:66][CH3:67])[N:60]([CH2:68][C:69]3[CH:70]=[CH:71][C:72]([C:75]4[CH:80]=[CH:79][CH:78]=[CH:77][C:76]=4[C:81]4[N:85]([C:86]([C:87]5[CH:92]=[CH:91][CH:90]=[CH:89][CH:88]=5)([C:99]5[CH:100]=[CH:101][CH:102]=[CH:103][CH:104]=5)[C:93]5[CH:94]=[CH:95][CH:96]=[CH:97][CH:98]=5)[N:84]=[N:83][N:82]=4)=[CH:73][CH:74]=3)[N:58]2[N:59]=1)[CH3:54].[CH2:1]([C:3]1[NH:4][C:5]2[N:6]([N:8]=[C:9]([CH2:13][O:14][CH3:15])[C:10]=2[CH2:11][CH3:12])[N:7]=1)[CH3:2]

Participants

4

Reactant 2

HCID 10532613HCID 10532613, compoundHCID 19002219HCID 19002219, compound2×

Product 2

HCID 10532613HCID 10532613, compoundHCID 178437913HCID 178437913, compound

Procedure

In the same manner as described in Example 66, 170 mg of 2,7-diethyl-6-methoxymethyl-1-[[2'-(N-triphenylmethyl tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-pyrazolo[1,5-b][1,2,4]triazole (compound 78a) and 2.5 g of 2,7-diethyl-6-methoxymethyl-5-[[2'-(N-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]-5H-pyrazolo[1,5-b][1,2,4]triazole (compound 78b) were obtained from 1.0 g of 2,7-diethyl-6-methoxymethyl-1H-pyrazolo[1,5-b][1,2,4]triazole.

Sources & evidence

ORD record
ord-2372635e1d234e5b9e676be32f1523ed
Source dataset
uspto-grants-1995_12
Patent number
US05475114

Reaction notes

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