反应详情

Dodecylamine (25.02 g, 0.13 moles) was heated at 85° C., and glycidol (10 g, 0.13 moles) was added dropwise. The reaction was heated under nitrogen for 3 hours then allowed to stir overnight. A white solid was recovered (crude yield=33.27 g), and the solid was recrystallized in hot hexane to give pure neosphingosine (yield=10.86 g).

1. temperatureThe reaction was heated under nitrogen for 3 hours
2. customA white solid was recovered (crude yield=33.27 g)
3. customthe solid was recrystallized in hot hexane
4. customto give pure neosphingosine (yield=10.86 g)