反应详情

N-(2,3-dihydroxypropyl)-hexadecylamine (1.0 g, 3.2 mmoles) and potassium hydroxide (0.01 g, 0.18 mmoles) were heated to 85° C. under vacuum and methyl-2-hydroxyoctanoate (0.55 g, 3.2 mmoles) was added dropwise to the reaction. The reaction was heated under vacuum for 6 hours. A waxy off white solid was obtained (crude yield=1,39 g), and the waxy solid further purified by recrystallization in hot hexane. (Yield=0.88g).

1. additionwas added dropwise to the reaction
2. temperatureThe reaction was heated under vacuum for 6 hours
3. customA waxy off white solid was obtained (crude yield=1,39 g)
4. customthe waxy solid further purified by recrystallization in hot hexane