Potassium Hydroxide → N-(2,3-dihydroxypropyl)-N-dodecyl-2-hydroxyhexadecanamide

HRID 2260092Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2260092
[OH:1][CH:2]([CH2:17][OH:18])[CH2:3][NH:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[OH-].[K+].CO[C:23](=[O:40])[CH:24]([OH:39])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38]>>[OH:1][CH:2]([CH2:17][OH:18])[CH2:3][N:4]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[C:23](=[O:40])[CH:24]([OH:39])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38]

Komponenten

4

Edukt 3

HCID 14797Potassium HydroxideHCID 1024961,2-Propanediol, 3-(dodecylamino)-HCID 543716Methyl 2-hydroxyhexadecanoate

Produkt 1

HCID 15825473N-(2,3-dihydroxypropyl)-N-dodecyl-2-hydroxyhexadecanamide

Versuchsvorschrift

N-(2,3-dihydroxypropyl)-N-dodecylamine (1.00 g, 0.0039 mole) and potassium hydroxide (0.01 g, 0.18 mmole) were heated to 85° C. under vacuum and methyl-2-hydroxyhexadecanoate (1.12 g, 0.0039 mole) was heated and added dropwise to the reaction. The reaction was heated under vacuum for 6 hours. A waxy off-white solid was obtained (crude yield=1.9 g). The waxy solid was recrystalized from hot hexane (yield=1.26 g).

Aufarbeitung

  1. temperaturewas heated
  2. additionadded dropwise to the reaction
  3. temperatureThe reaction was heated under vacuum for 6 hours
  4. customA waxy off-white solid was obtained (crude yield=1.9 g)
  5. customThe waxy solid was recrystalized from hot hexane (yield=1.26 g)

Quellen und Nachweise

ORD-Eintrag
ord-26d0ed40d8fa420097c96f1ceb2f5512
Quelldatensatz
uspto-grants-1995_12
Patentnummer
US05476671

Notizen zur Reaktion

Wird geladen…