N-Ethylpyridine-4-methylamine → HCID 54137422, compound

HRID 2260430Notes

Reaction equation

C(NC[C:5]1[CH:10]=[CH:9][N:8]=[CH:7][CH:6]=1)C.[CH3:11][C:12]([C:15]1[CH:16]=[C:17]([S:25][C@@H:26]2[CH2:31][CH2:30][CH2:29][CH2:28][C@H:27]2[S:32][CH2:33][C:34]([N:36]([CH3:45])[CH2:37][CH2:38]C2C=CC=CN=2)=[O:35])[CH:18]=[C:19]([C:21]([CH3:24])([CH3:23])[CH3:22])[CH:20]=1)([CH3:14])[CH3:13]>>[CH3:22][C:21]([C:19]1[CH:18]=[C:17]([S:25][C@@H:26]2[CH2:31][CH2:30][CH2:29][CH2:28][C@H:27]2[S:32][CH2:33][C:34]([N:36]([CH2:37][CH3:38])[CH2:45][C:5]2[CH:10]=[CH:9][N:8]=[CH:7][CH:6]=2)=[O:35])[CH:16]=[C:15]([C:12]([CH3:13])([CH3:11])[CH3:14])[CH:20]=1)([CH3:23])[CH3:24]

Participants

Reactant 2

HCID 96681N-Ethylpyridine-4-methylamine

HCID 15287679HCID 15287679, compound

Product 1

HCID 54137422HCID 54137422, compound

Procedure

Substituting 4-(ethylaminomethyl)pyridine for the 2-(2-methylaminoethyl)pyridine of Example 16, and following the procedure described therein, gives trans-2-[[2-[[3,5-bis(1,1-dimethylethyl)phenyl]thio]cyclohexyl]thio]-N-ethyl-N-(4-pyridinylmethyl)acetamide.

Sources & evidence

ORD record: ord-4ed949c4fea440fd8d53aeddbf393cb8
Source dataset: uspto-grants-1995_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05476944

Reaction notes

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