HRID2260431

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID122425

5-Nitro-2-pyridylaminoethyl-2-amine

C7H10N4O2

结构：CN(CCc1ccccn1)C(=O)CS[C@@H]1CCCC[C@H]1Sc1cc(C(C)(C)C)cc(C(C)(C)C)c1

HCID15287679

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)c1cc(S[C@@H]2CCCC[C@H]2SCC(=O)NCCNc2ccc([N+](=O)[O-])cn2)cc(C(C)(C)C)c1

HCID53817346

未命名化合物

PROCEDURE

实验过程

Substituting 2-(2-aminoethylamino)-5-nitropyridine for the 2-(2-methylaminoethyl)pyridine of Example 16, and following the procedure described therein, gives trans-2-[[2-[[3,5-bis(1,1-dimethylethyl)phenyl]thio]cyclohexyl]thio]-N-[[(5-nitropyridin-2-yl)amino]ethyl]acetamide.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cfb7afbeb3cc41539b6658347857a240
来源数据集: uspto-grants-1995_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05476944
来源说明: uspto-grants-1995_12

反应 SMILES

[NH2:1][CH2:2][CH2:3][NH:4][C:5]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][N:6]=1.[CH3:14][C:15]([C:18]1[CH:19]=[C:20]([S:28][C@@H:29]2[CH2:34][CH2:33][CH2:32][CH2:31][C@H:30]2[S:35][CH2:36][C:37](N(C)CCC2C=CC=CN=2)=[O:38])[CH:21]=[C:22]([C:24]([CH3:27])([CH3:26])[CH3:25])[CH:23]=1)([CH3:17])[CH3:16]>>[CH3:27][C:24]([C:22]1[CH:21]=[C:20]([S:28][C@@H:29]2[CH2:34][CH2:33][CH2:32][CH2:31][C@H:30]2[S:35][CH2:36][C:37]([NH:1][CH2:2][CH2:3][NH:4][C:5]2[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][N:6]=2)=[O:38])[CH:19]=[C:18]([C:15]([CH3:14])([CH3:16])[CH3:17])[CH:23]=1)([CH3:25])[CH3:26]