2-Pyridineethanamine → HCID 54406860, compound

HRID 2260433Notes

Reaction equation

NCCC1C=CC=CN=1.[CH3:10][C:11]([C:14]1[CH:15]=[C:16]([S:24][C@@H:25]2[CH2:30][CH2:29][CH2:28][CH2:27][C@H:26]2[S:31][CH2:32][C:33]([N:35](C)[CH2:36][CH2:37][C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][N:39]=2)=[O:34])[CH:17]=[C:18]([C:20]([CH3:23])([CH3:22])[CH3:21])[CH:19]=1)([CH3:13])[CH3:12]>>[CH3:13][C:11]([C:14]1[CH:15]=[C:16]([S:24][C@@H:25]2[CH2:30][CH2:29][CH2:28][CH2:27][C@H:26]2[S:31][CH2:32][C:33]([NH:35][CH2:36][CH2:37][C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][N:39]=2)=[O:34])[CH:17]=[C:18]([C:20]([CH3:21])([CH3:22])[CH3:23])[CH:19]=1)([CH3:10])[CH3:12]

Participants

Reactant 2

HCID 759192-Pyridineethanamine

HCID 15287679HCID 15287679, compound

Product 1

HCID 54406860HCID 54406860, compound

Procedure

Substituting 2-(2-aminoethyl)pyridine for the 2-(2-methylaminoethyl)pyridine of Example 16, and following the procedure described therein, gives trans-2-[[2-[[3,5-bis(1,1-dimethylethyl)phenyl]thio]cyclohexyl]thio]-N-(2-pyridinylethyl)acetamide.

Sources & evidence

ORD record: ord-1c3e374d383a45419aec80e830292067
Source dataset: uspto-grants-1995_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05476944

Reaction notes

Loading…