4-Pyridinemethanamine → N-(4-Pyridinylmethyl)acetamide

HRID 2260436Notes

Reaction equation

HRID 2260436 reaction equation
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1.CC(C1C=C(S[C@@H]2CCCC[C@H]2S[CH2:31][C:32](N(C)CCC2C=CC=CN=2)=[O:33])C=C(C(C)(C)C)C=1)(C)C>>[N:6]1[CH:7]=[CH:8][C:3]([CH2:2][NH:1][C:32](=[O:33])[CH3:31])=[CH:4][CH:5]=1

Participants

3

Reactant 2

HCID 773174-PyridinemethanamineHCID 15287679HCID 15287679, compound

Product 1

HCID 289830N-(4-Pyridinylmethyl)acetamide

Procedure

Substituting 4-(aminomethyl)pyridine for the 2-(2-methylaminoethyl)pyridine of Example 16, and following the procedure described therein, gives trans-2-[[2-[3,5-bis(1,1-dimethylethyl)phenyl]thio]cyclohexyl]thio]-N-(4-pyridinylmethyl)-acetamide.

Sources & evidence

ORD record
ord-eb42c8f5aa1547b8bdece7f4855ff0eb
Source dataset
uspto-grants-1995_12
Patent number
US05476944

Reaction notes

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