HCID 22857993, compound → HCID 22857989, compound

HRID 2260438Notes

Reaction equation

HRID 2260438 reaction equation
[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([S:15][C@H:16]2[CH2:20][CH2:19][CH2:18][C@H:17]2[OH:21])[CH:8]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:10]=1)([CH3:4])[CH3:3].CC(C1C=C(S[C@@H]2CC[CH2:39][C@H:38]2[OH:42])C=C(C(C)(C)C)C=1)(C)C.CC(C1C=C(C(C)(C)C)C=CC=1S[C@H]1CCC[C@H]1[OH:63])(C)C>C(Cl)(Cl)Cl>[CH3:14][C:11]([C:9]1[CH:8]=[C:7]([S:15][C@H:16]2[CH2:20][CH2:19][CH2:18][C@H:17]2[O:21][CH2:39][C:38]([OH:42])=[O:63])[CH:6]=[C:5]([C:2]([CH3:1])([CH3:3])[CH3:4])[CH:10]=1)([CH3:12])[CH3:13]

Participants

5

Reactant 3

HCID 22857993HCID 22857993, compoundHCID 22857994HCID 22857994, compoundHCID 22858007HCID 22858007, compound

Product 1

HCID 22857989HCID 22857989, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared by the method described in Example 77, except that the title product of Example 83 was substituted for the title product of Example 75, Compound A. The structure was supported by NMR, optical rotation (CHCl3, 25° C.; 589 nm -64.0°±2.80°; 365 nm -208.1°±6.04) and elemental analysis.

Sources & evidence

ORD record
ord-aec8fd163918422596f10ad62dbb7e10
Source dataset
uspto-grants-1995_12
Patent number
US05476944

Reaction notes

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