HCID 22857993, compound → HCID 22857991, compound

HRID 2260439Notes

Reaction equation

HRID 2260439 reaction equation
[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([S:15][C@@H:16]2[CH2:21][CH2:20][CH2:19][CH2:18][C@H:17]2[OH:22])[CH:8]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:10]=1)([CH3:4])[CH3:3].CC(C1C=C(S[C@@H]2CC[CH2:40][C@H:39]2[OH:43])C=C(C(C)(C)C)C=1)(C)C.CC(C1C=C(C(C)(C)C)C=CC=1S[C@H]1CCC[C@H]1[OH:64])(C)C>C(Cl)(Cl)Cl>[CH3:14][C:11]([C:9]1[CH:8]=[C:7]([S:15][C@@H:16]2[CH2:21][CH2:20][CH2:19][CH2:18][C@H:17]2[O:22][CH2:40][C:39]([OH:43])=[O:64])[CH:6]=[C:5]([C:2]([CH3:1])([CH3:3])[CH3:4])[CH:10]=1)([CH3:12])[CH3:13]

Participants

5

Reactant 3

HCID 22857993HCID 22857993, compoundHCID 22858007HCID 22858007, compoundHCID 22858010HCID 22858010, compound

Product 1

HCID 22857991HCID 22857991, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared by the method described in Example 77, except that the title product of Example 87 was substituted for the title product of Example 75, Compound A. The structure was supported by NMR, Ir optical rotation (CHCl3, 25° C.; 589 nm -42.5°±2.69°; 365 nm 138.4°±18.1°) and elemental analysis.

Sources & evidence

ORD record
ord-b793428b33a5462f8a34f6135422913f
Source dataset
uspto-grants-1995_12
Patent number
US05476944

Reaction notes

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