HCID 22857993, compound → HCID 22857990, compound

HRID 2260442Notes

Reaction equation

HRID 2260442 reaction equation
[CH3:1][C:2]([C:5]1[CH:10]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:8]=[CH:7][C:6]=1[S:15][C@@H:16]1[CH2:20][CH2:19][CH2:18][C@H:17]1[OH:21])([CH3:4])[CH3:3].CC(C1C=C(S[C@@H]2CC[CH2:39][C@H:38]2[OH:42])C=C(C(C)(C)C)C=1)(C)C.CC(C1C=C(C(C)(C)C)C=CC=1S[C@H]1CCC[C@H]1[OH:63])(C)C>C(Cl)(Cl)Cl>[CH3:4][C:2]([C:5]1[CH:10]=[C:9]([C:11]([CH3:12])([CH3:13])[CH3:14])[CH:8]=[CH:7][C:6]=1[S:15][C@@H:16]1[CH2:20][CH2:19][CH2:18][C@H:17]1[O:21][CH2:39][C:38]([OH:42])=[O:63])([CH3:1])[CH3:3]

Participants

5

Reactant 3

HCID 22857993HCID 22857993, compoundHCID 22858006HCID 22858006, compoundHCID 22858007HCID 22858007, compound

Product 1

HCID 22857990HCID 22857990, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared by the method described in Example 77, except that the title product of Example 91 was substituted for the title product of Example 75, Compound A. The structure was supported by NMR, Ir, optical rotation (CHCl3, 25° C.; 589 nm +1.91°±2.69°; 365 nm -28.2°±18.1°) and elemental analysis.

Sources & evidence

ORD record
ord-288eece4ec4847d7af0a2836721fab72
Source dataset
uspto-grants-1995_12
Patent number
US05476944

Reaction notes

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