1-Chloro-2-nitrobenzene → 1-Fluoro-2-nitrobenzene

Participants

Reaction Conditions

Reaction Steps

In a 2-liter flange flask fitted with a distillation bridge and impeller stirrer, 278.4 g (4.8 mol) of potassium fluoride and 23.5 g (0.21 mol) of tetramethylammonium chloride were introduced at 120° C. into the melt of 939 g (6.0 mol) of 2-chloronitrobenzene. Subsequently, 4 g (0.38 mol) of xylene were added and the reaction suspension was heated to 180° C., the xylene was removed under reduced pressure and the mixture was stirred for 21 hours at this temperature. Amount of 2-fluoronitrobenzene formed, according to GC analysis:

Provenance & Evidence