Heptafluorobutyryl Chloride → HCID 18997741, compound

HRID 2260468Notes

Reaction equation

HRID 2260468 reaction equation
[CH2:1]([O:11][C:12]1[CH:21]=[CH:20][C:15]([C:16]([NH:18][NH2:19])=[O:17])=[CH:14][CH:13]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[F:22][C:23]([F:34])([F:33])[C:24]([F:32])([F:31])[C:25]([F:30])([F:29])[C:26](Cl)=[O:27]>N1C=CC=CC=1>[CH2:1]([O:11][C:12]1[CH:21]=[CH:20][C:15]([C:16]([NH:18][NH:19][C:26](=[O:27])[C:25]([F:29])([F:30])[C:24]([F:31])([F:32])[C:23]([F:34])([F:33])[F:22])=[O:17])=[CH:14][CH:13]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

4

Reactant 2

HCID 67810Heptafluorobutyryl ChlorideHCID 4401632HCID 4401632, compound

Product 1

HCID 18997741HCID 18997741, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

46.8 g of 4-n-decyloxybenzoic acid hydrazide are dissolved in 320 ml of pyridine. 23.7 ml of heptafluorobutyric acid chloride are added dropwise at room temperature and the mixture is stirred for a further 11/2 hours. It is then poured on 1600 ml of ice/water, and the crystals are filtered off with suction and rinsed with water. Recrystallization from toluene gives 39.9 g of N-(4-n-decyloxybenzoyl)-N'-heptafluorobutyrylhydrazine of melting point 88° C.

Workup

  1. filtrationthe crystals are filtered off with suction
  2. washrinsed with water
  3. customRecrystallization from toluene

Sources & evidence

ORD record
ord-010e0dfbab27497eba9481c5648c0ff1
Source dataset
uspto-grants-1995_12
Patent number
US05478496

Reaction notes

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