2,6-Dichloroaniline → HCID 10023756, compound

HRID 2260578Notes

Reaction equation

HRID 2260578 reaction equation
[CH3:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][CH2:7][C:8]3[CH:17]=[CH:16][CH:15]=[CH:14][C:9]=3[CH:10]([C:11]([OH:13])=O)[C:4]=2[CH:3]=1.[Cl:20][C:21]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:22]=1[NH2:23]>>[Cl:20][C:21]1[CH:27]=[CH:26][CH:25]=[C:24]([Cl:28])[C:22]=1[NH:23][C:11]([CH:10]1[C:9]2[CH:14]=[CH:15][CH:16]=[CH:17][C:8]=2[CH2:7][O:6][C:5]2[CH:18]=[CH:19][C:2]([CH3:1])=[CH:3][C:4]1=2)=[O:13]

Participants

3

Reactant 2

HCID 118462,6-DichloroanilineHCID 101063426,11-Dihydro-2-methyldibenz[b,e]-oxepin-11-carboxylic acid

Product 1

HCID 10023756HCID 10023756, compoundYield 88.1%

Procedure

The similar procedures as in Example 1 were repeated except using 1.0 g of Compound A and 0.76 g of 2,6-dichloroaniline in place of aniline to obtain 1.38 g of Compound 6.

Sources & evidence

ORD record
ord-54d248be992f4beb92bb91ee4a0c99f0
Source dataset
uspto-grants-1995_12
Patent number
US05478835

Reaction notes

Loading…