2,6-Dibromoaniline → N-(2,6-Dibromophenyl)-6,11-dihydro-2-methyldibenz[b,e]-oxepin-11-carboxamide

HRID 2260579Notes

Reaction equation

HRID 2260579 reaction equation
[CH3:1][C:2]1[CH:19]=[CH:18][C:5]2[O:6][CH2:7][C:8]3[CH:17]=[CH:16][CH:15]=[CH:14][C:9]=3[CH:10]([C:11]([OH:13])=O)[C:4]=2[CH:3]=1.[Br:20][C:21]1[CH:27]=[CH:26][CH:25]=[C:24]([Br:28])[C:22]=1[NH2:23]>>[Br:20][C:21]1[CH:27]=[CH:26][CH:25]=[C:24]([Br:28])[C:22]=1[NH:23][C:11]([CH:10]1[C:9]2[CH:14]=[CH:15][CH:16]=[CH:17][C:8]=2[CH2:7][O:6][C:5]2[CH:18]=[CH:19][C:2]([CH3:1])=[CH:3][C:4]1=2)=[O:13]

Participants

3

Reactant 2

HCID 690982,6-DibromoanilineHCID 101063426,11-Dihydro-2-methyldibenz[b,e]-oxepin-11-carboxylic acid

Product 1

HCID 10435533N-(2,6-Dibromophenyl)-6,11-dihydro-2-methyldibenz[b,e]-oxepin-11-carboxamideYield 58.7%

Procedure

The similar procedures as in Example 1 were repeated except using 1.40 g of Compound A and 1.28 g of 2,6-dibromoaniline in place of aniline to obtain 1.46 g of Compound 7.

Sources & evidence

ORD record
ord-1da80c6d0ea24e85b438ad2a59ed08c8
Source dataset
uspto-grants-1995_12
Patent number
US05478835

Reaction notes

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