2,6-Dichloroaniline → HCID 11743950, compound

HRID 2260598Notes

Reaction equation

HRID 2260598 reaction equation
[C:1]([C:5]1[CH:22]=[CH:21][C:8]2[O:9][CH2:10][C:11]3[CH:20]=[CH:19][CH:18]=[CH:17][C:12]=3[CH:13]([C:14](O)=[O:15])[C:7]=2[CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[Cl:23][C:24]1[CH:30]=[CH:29][CH:28]=[C:27]([Cl:31])[C:25]=1[NH2:26]>>[C:1]([C:5]1[CH:22]=[CH:21][C:8]2[O:9][CH2:10][C:11]3[CH:20]=[CH:19][CH:18]=[CH:17][C:12]=3[CH:13]([C:14]([NH:26][C:25]3[C:24]([Cl:23])=[CH:30][CH:29]=[CH:28][C:27]=3[Cl:31])=[O:15])[C:7]=2[CH:6]=1)([CH3:2])([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 118462,6-DichloroanilineHCID 10379826HCID 10379826, compound2×

Product 1

HCID 11743950HCID 11743950, compoundYield 69.1%

Procedure

The similar procedures as in Example 1 were repeated except using 1.0 g of 2-(tert-butyl)-6,11-dihydrodibenz[b,e]oxepine-11-carboxylic acid obtained in Example 42 (Compound D) in place of Compound A and 0.49 g of 2,6-dichloroaniline in place of aniline to obtain 0.92 g of Compound 45.

Sources & evidence

ORD record
ord-5a3ea50ec4c5481d91096548fdb4244e
Source dataset
uspto-grants-1995_12
Patent number
US05478835

Reaction notes

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