1-Methyl-6-sulfanyl-1,2,3,4-tetrahydroquinolin-2-one → HCID 9822528, compound

Participants

Reaction Steps

Using an analogous procedure to that described in Example 1, 6-mercapto-1-methyl-1,2,3,4-tetrahydroquinolin-2-one was reacted with (2S,4R)-4-(2-chlorothiazol-5-yl)-4-methoxy-2-methyltetrahydropyran to give (2S,4R)-4-methoxy-2-methyl-4-[2-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-ylthio)thiazol-5-yl]tetrahydropyran in 95Z yield as a foam;

Provenance & Evidence