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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2260713Generated: October 28, 2026

4-Fluorobenzaldehyde → 4-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethoxy]benzaldehyde

https://huagongshe.com/reaction/2260713

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzaldehydeHCID 68023—
ReactantN-(2-Hydroxyethyl)phthalimideHCID 77499—
Product4-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethoxy]benzaldehydeHCID 12810641—

Reaction Steps

The title compound, mp 138° C., was prepared from N-(2-hydroxyethyl)phthalimide (9.6 g) and 4-fluorobenzaldehyde (6.2 g, 5.3 ml) by a procedure similar to that described in Procedure 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05478851
Source datasetuspto-grants-1995_12
ORD IDord-01ff4d7cb1ea4675926b6b47eb5771ad
Source noteuspto-grants-1995_12