Citric Acid → HCID 86749178, compound

HRID 2260790Notes

Reaction equation

HRID 2260790 reaction equation
[C:1]([O-:8])(=[O:7])/[CH:2]=[CH:3]\[C:4]([OH:6])=[O:5].[NH4+:9].[C:10]([OH:22])(=[O:21])[CH2:11][C:12]([CH2:17][C:18]([OH:20])=[O:19])([C:14]([OH:16])=[O:15])[OH:13].[Al].[OH-].[Na+]>>[NH2:9][C@H:2]([C:1]([OH:8])=[O:7])[CH2:3][C:4]([OH:6])=[O:5].[C:10]([OH:22])(=[O:21])[CH2:11][C:12]([CH2:17][C:18]([OH:20])=[O:19])([C:14]([OH:16])=[O:15])[OH:13]

Participants

5

Reactant 4

HCID 311Citric AcidHCID 14798Sodium HydroxideHCID 5359268AluminumHCID 1159344144742-89-4

Product 1

HCID 86749178HCID 86749178, compound

Procedure

Monoammonium maleate (2,627 g of 94% concentration wet salt, 0.0186 mole) and citric acid (0,395 g, 0.0021 mole) were ground together and thoroughly mixed to form a slightly wetted mass. This mixture was placed in the aluminum reaction vessel to form a layer and then was heated at about 240°-260° C. for 40 minutes in a convection oven. The resulting product was a red-brown solid foam, weight 1.991 g, representing 92% theoretical yield of polysuccinimidecitric acid copolymer. Hydrolysis of this product with sodium hydroxide at room temperature produced an aspartic acid-citric acid copolymer having molecular weights by GPC of Mw 1196, Mn 613, Mw/Mn 1.95.

Workup

  1. additionthoroughly mixed
  2. customto form a slightly wetted mass
  3. customto form a layer
  4. temperaturewas heated at about 240°-260° C. for 40 minutes in a convection oven

Sources & evidence

ORD record
ord-e82bcdeef48e4f649cc31cc69f1dbab9
Source dataset
uspto-grants-1995_12
Patent number
US05478919

Reaction notes

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