HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 1-(1-Amidino-4-piperidinyl)-3-[4-(2-methoxycarbonyl-ethyl)-phenyl]-imidazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | S-Ethylisothiuronium bromide | HCID 200213 | — |
| Reactant | 1-[4-(2-Methoxycarbonyl-ethyl)-phenyl]-3-(4-piperidinyl)-imidazolidin-2-one | HCID 22098470 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-(1-Amidino-4-piperidinyl)-3-[4-(2-methoxycarbonyl-ethyl)-phenyl]-imidazolidin-2-one | HCID 53763634 | — |
Reaction Steps
Prepared from 1-[4-(2-methoxycarbonyl-ethyl)-phenyl]-3-(4-piperidinyl)-imidazolidin-2-one and S-ethylisothiourea-hydrobromide by heating to 100° C. for four hours in dimethylformamide in the presence of sodium carbonate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05478942 |
| Source dataset | uspto-grants-1995_12 |
| ORD ID | ord-80d011d9e81448508e2db6d349fe5b53 |
| Source note | uspto-grants-1995_12 |