反应详情

Under a nitrogen atmosphere, one drop of pyridine was added to 10 g of 5,9,13,17-tetramethyloctadecanoic acid and 20 ml of methylene chloride, and 5.2 g of thionyl chloride was added dropwise thereto at room temperature. After the completion of dropwise addition, the mixture was refluxed for 1 hour and concentrated under reduced pressure to obtain 10.5 g of 5,9,13,17-tetramethyloctadecanoic acid chloride.

1. additionwas added dropwise
2. customat room temperature
3. additionAfter the completion of dropwise addition
4. temperaturethe mixture was refluxed for 1 hour
5. concentrationconcentrated under reduced pressure