Thionyl Chloride → HCID 86239094, compound

HRID 2260957Notes

Reaction equation

HRID 2260957 reaction equation
[CH3:1][CH:2]([CH2:9][CH2:10][CH2:11][CH:12]([CH3:24])[CH2:13][CH2:14][CH2:15][CH:16]([CH3:23])[CH2:17][CH2:18][CH2:19][CH:20]([CH3:22])[CH3:21])[CH2:3][CH2:4][CH2:5][C:6](O)=[O:7].S(Cl)([Cl:27])=O>N1C=CC=CC=1.C(Cl)Cl>[CH3:1][CH:2]([CH2:9][CH2:10][CH2:11][CH:12]([CH3:24])[CH2:13][CH2:14][CH2:15][CH:16]([CH3:23])[CH2:17][CH2:18][CH2:19][CH:20]([CH3:22])[CH3:21])[CH2:3][CH2:4][CH2:5][C:6]([Cl:27])=[O:7]

Participants

5

Reactant 2

HCID 24386Thionyl ChlorideHCID 19050536HCID 19050536, compound

Product 1

HCID 86239094HCID 86239094, compoundYield 99.6%

Reagents, catalysts & solvents 2

HCID 1049PyridineCatalystHCID 6344DichloromethaneSolvent

Procedure

Under a nitrogen atmosphere, one drop of pyridine was added to 10 g of 5,9,13,17-tetramethyloctadecanoic acid and 20 ml of methylene chloride, and 5.2 g of thionyl chloride was added dropwise thereto at room temperature. After the completion of dropwise addition, the mixture was refluxed for 1 hour and concentrated under reduced pressure to obtain 10.5 g of 5,9,13,17-tetramethyloctadecanoic acid chloride.

Workup

  1. additionwas added dropwise
  2. customat room temperature
  3. additionAfter the completion of dropwise addition
  4. temperaturethe mixture was refluxed for 1 hour
  5. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-720445fd21ab4c9b902e88a71fcedd32
Source dataset
uspto-grants-2010_12
Patent number
US07846903B2

Reaction notes

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