Pyridine → 2-Pyridyl Trifluoromethanesulfonate

Participants

Reaction Steps

In analogy to GP 2, reaction of 11.3 g Intermediate 1.8 (47 mmol, 1 eq.), 5.6 mL dry pyridine (70 mmol, 1.5 eq.), 12 ml trifluoromethanesulfonic acid anhydride (70 mmol, 1.5 eq.) in 450 mL DCM yielded 12.2 g 2-pyridyl triflate (33 mmol, 70% yield).

Provenance & Evidence