Thiazolidinedione → 5-[(Quinolin-6-yl)methylidene]-1,3-thiazolidine-2,4-dione

HRID 2261119Notes

Reaction equation

[N:1]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]=O)=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[S:13]1[CH2:17][C:16](=[O:18])[NH:15][C:14]1=[O:19]>>[N:1]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]=[C:17]3[S:13][C:14](=[O:19])[NH:15][C:16]3=[O:18])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

Reactant 2

HCID 5437Thiazolidinedione

HCID 7656536-Quinolinecarbaldehyde2×

Product 1

HCID 569469415-[(Quinolin-6-yl)methylidene]-1,3-thiazolidine-2,4-dione

Procedure

Following the general method as outlined in Example 1, starting from quinoline-6-carbaldehyde (intermediate 5) and 1,3-thiazolidine-2,4-dione, the title compound was obtained.

Sources & evidence

ORD record: ord-c229e70dfe634f4c82be44b91269fc49
Source dataset: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07846925B2

Reaction notes

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