Thiazolidinedione → 5-(6-Quinoxalinylmethylene)-2,4-thiazolidinedione

HRID 2261133Notes

Reaction equation

[N:1]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]=O)=[CH:8][CH:9]=2)[N:4]=[CH:3][CH:2]=1.[CH2:13]1[S:19][C:17](=[O:18])[NH:16][C:14]1=[O:15]>>[N:1]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]=[C:13]3[S:19][C:17](=[O:18])[NH:16][C:14]3=[O:15])=[CH:8][CH:9]=2)[N:4]=[CH:3][CH:2]=1

Participants

Reactant 2

HCID 5437Thiazolidinedione

HCID 763958Quinoxaline-6-carboxaldehyde2×

Product 1

HCID 249062735-(6-Quinoxalinylmethylene)-2,4-thiazolidinedione

Procedure

Following the general method as outlined in Example 1, starting from quinoxaline-6-carbaldehyde (intermediate 55) and thiazolidinedione, the title compound was obtained.

Sources & evidence

ORD record: ord-22612f1f674e4b77ba85e9d28874a439
Source dataset: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07846925B2

Reaction notes

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