Quinoxaline-6-carboxaldehyde → 5-[(Quinoxalin-6-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

HRID 2261134Notes

Reaction equation

[N:1]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]=O)=[CH:8][CH:9]=2)[N:4]=[CH:3][CH:2]=1.[S:13]1[CH2:19][C:17](=[O:18])[NH:16][C:14]1=[S:15]>>[N:1]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]=[C:19]3[S:13][C:14](=[S:15])[NH:16][C:17]3=[O:18])=[CH:8][CH:9]=2)[N:4]=[CH:3][CH:2]=1

Participants

Reactant 2

HCID 763958Quinoxaline-6-carboxaldehyde2×

HCID 1201546Rhodanine

Product 1

HCID 713782515-[(Quinoxalin-6-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

Procedure

Following the general method as outlined in Example 1, starting from quinoxaline-6-carbaldehyde (intermediate 55) and rhodanine, the title compound was obtained.

Sources & evidence

ORD record: ord-4e417bc263644db28d85d2e3fc5a5c1c
Source dataset: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07846925B2

Reaction notes

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