Thiazolidinedione → HCID 72334352, compound

HRID 2261145Notes

Reaction equation

[C:1]([O:5][C:6]([N:8]1[C:13]2[CH:14]=[C:15]([CH:18]=O)[CH:16]=[CH:17][C:12]=2[O:11][CH:10]=[CH:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[S:20]1[CH2:24][C:23](=[O:25])[NH:22][C:21]1=[O:26]>>[C:1]([O:5][C:6]([N:8]1[C:13]2[CH:14]=[C:15]([CH:18]=[C:24]3[S:20][C:21](=[O:26])[NH:22][C:23]3=[O:25])[CH:16]=[CH:17][C:12]=2[O:11][CH:10]=[CH:9]1)=[O:7])([CH3:2])([CH3:3])[CH3:4]

Participants

Reactant 2

HCID 5437Thiazolidinedione

HCID 59592653HCID 59592653, compound2×

Product 1

HCID 72334352HCID 72334352, compound

Procedure

Following the general method as outlined in Example 1, starting from 6-Formyl-benzo[1,4]oxazine-4-carboxylic acid tert-butyl ester (intermediate 63) and 1,3-thiazolidine-2,4-dione, the title compound was obtained.

Sources & evidence

ORD record: ord-60474b070bf54092824918fe4dbeb168
Source dataset: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07846925B2

Reaction notes

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