Thiazolidinedione → HCID 76529649, compound

HRID 2261148Notes

Reaction equation

[CH2:1]([N:8]1[C:13]2[CH:14]=[C:15]([CH:18]=O)[CH:16]=[CH:17][C:12]=2[O:11][CH2:10][C:9]1=[O:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:21]1[CH2:25][C:24](=[O:26])[NH:23][C:22]1=[O:27]>>[CH2:1]([N:8]1[C:13]2[CH:14]=[C:15]([CH:18]=[C:25]3[S:21][C:22](=[O:27])[NH:23][C:24]3=[O:26])[CH:16]=[CH:17][C:12]=2[O:11][CH2:10][C:9]1=[O:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 5437Thiazolidinedione

HCID 28320623HCID 28320623, compound2×

Product 1

HCID 76529649HCID 76529649, compound

Procedure

Following the general method as outlined in Example 1, starting from 4-Benzyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbaldehyde (intermediate 66) and 1,3-thiazolidine-2,4-dione, the title compound was obtained.

Sources & evidence

ORD record: ord-8ea24dfbea8e4e8f999e1a2a9e6a57cd
Source dataset: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07846925B2

Reaction notes

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