Thiazolidinedione → 5-[(2-Chloro-1-benzofuran-5-yl)methylidene]-1,3-thiazolidine-2,4-dione

HRID 2261149Notes

Reaction equation

HRID 2261149 reaction equation
[Cl:1][C:2]1[O:3][C:4]2[CH:10]=[CH:9][C:8]([CH:11]3OCCO3)=[CH:7][C:5]=2[CH:6]=1.[S:16]1[CH2:20][C:19](=[O:21])[NH:18][C:17]1=[O:22]>>[Cl:1][C:2]1[O:3][C:4]2[CH:10]=[CH:9][C:8]([CH:11]=[C:20]3[S:16][C:17](=[O:22])[NH:18][C:19]3=[O:21])=[CH:7][C:5]=2[CH:6]=1

Participants

3

Reactant 2

HCID 5437ThiazolidinedioneHCID 574696732-Chloro-5-(1,3-dioxolan-2-yl)benzofuran2×

Product 1

HCID 713782475-[(2-Chloro-1-benzofuran-5-yl)methylidene]-1,3-thiazolidine-2,4-dione

Procedure

Following the general method as outlined in Example 1, starting from 2-Chloro-5-[1,3]dioxolan-2-yl-benzofurane (intermediate 67) and 1,3-thiazolidine-2,4-dione, the title compound was obtained.

Sources & evidence

ORD record
ord-e71c6975ca5946698c9f1b7d9383aad8
Source dataset
uspto-grants-2010_12
Patent number
US07846925B2

Reaction notes

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