Thiazolidinedione → 5-{[3-(Phenylethynyl)-1-benzofuran-5-yl]methylidene}-1,3-thiazolidine-2,4-dione

HRID 2261151Notes

Reaction equation

HRID 2261151 reaction equation
[C:1]1([C:7]#[C:8][C:9]2[C:13]3[CH:14]=[C:15]([CH:18]=O)[CH:16]=[CH:17][C:12]=3[O:11][CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[S:20]1[CH2:24][C:23](=[O:25])[NH:22][C:21]1=[O:26]>>[C:1]1([C:7]#[C:8][C:9]2[C:13]3[CH:14]=[C:15]([CH:18]=[C:24]4[S:20][C:21](=[O:26])[NH:22][C:23]4=[O:25])[CH:16]=[CH:17][C:12]=3[O:11][CH:10]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 5437ThiazolidinedioneHCID 574696653-(Phenylethynyl)-1-benzofuran-5-carbaldehyde2×

Product 1

HCID 713782455-{[3-(Phenylethynyl)-1-benzofuran-5-yl]methylidene}-1,3-thiazolidine-2,4-dione

Procedure

Following the general method as outlined in Example 1, starting from 3-Phenylethynyl-benzofuran-5-carbaldehyde (intermediate 59) and 1,3-thiazolidine-2,4-dione, the title compound was obtained.

Sources & evidence

ORD record
ord-29e16cffc664410da347d156a3bdbd78
Source dataset
uspto-grants-2010_12
Patent number
US07846925B2

Reaction notes

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