HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromo-3H-oxazolo(4,5-b)pyridin-2-one → 6-Bromo-3-(4-methylpiperidine-1-carbonyl)-3H-oxazolo[4,5-b]pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromo-3H-oxazolo(4,5-b)pyridin-2-one | HCID 13614458 | — |
| Reactant | 4-Methylpiperidine-1-carbonyl Chloride | HCID 15221516 | — |
| Product | 6-Bromo-3-(4-methylpiperidine-1-carbonyl)-3H-oxazolo[4,5-b]pyridin-2-one | HCID 11998452 | — |
Reaction Steps
100 mg (0.46 mmol) of 6-bromo-3H-oxazolo[4,5-b]pyridin-2-one were reacted in analogy to Example 6 with 150 mg (0.93 mmol) of 4-methylpiperidin-1-carbonyl chloride. Yield: 78 mg (50%), M+H+: 340.09.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07846943B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-29d67c2a2f564be494c970cc0cf90373 |
| Source note | uspto-grants-2010_12 |