Ethanol → HCID 178469309, compound

Participants

Reaction Conditions

Reaction Steps

4-Ethylamino-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde (1 g, 5.3 mmol) and 3-cyanomethyl-5-methoxy-benzoic acid ethyl ester (1.3 g, 5.8 mmol) are dissolved in ethanol (4 mL) and piperidine (2 mL, 21.2 mmol) is added at room temperature. The reaction mixture is heated at 120° C. and stirred for 24 h. The reaction mixture is then concentrated and dried to yield the crude product. The crude product is used for the next step without any further purification. MS m/z 391.1 (M+1).

Provenance & Evidence