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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2261205Generated: November 3, 2026

2-Fluoro-4-hydroxybenzoic Acid → (2-Fluoro-4-hydroxy-phenyl)-[2-(S)(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone

https://huagongshe.com/reaction/2261205

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-hydroxybenzoic AcidHCID 2783398—
Reactant(R)-2-methyl-1-((S)-pyrrolidin-2-ylmethyl)pyrrolidineHCID 46911921—
Product(2-Fluoro-4-hydroxy-phenyl)-[2-(S)(2-(R)-methyl-pyrrolidin-1-ylmethyl)-pyrrolidin-1-yl]-methanoneHCID 11960537—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedure A from 2-Fluoro-4-hydroxy-benzoic acid and 2-(R)-methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine. MS (ES+) m/e 307.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07846950B2
Source datasetuspto-grants-2010_12
ORD IDord-93f834fc51db462db1f8c82191f3ea10
Source noteuspto-grants-2010_12