HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine → (2-Fluoro-4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine | HCID 853152 | — |
| Reactant | 2-Fluoro-4-hydroxybenzoic Acid | HCID 2783398 | — |
| Product | (2-Fluoro-4-hydroxy-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone | HCID 59259534 | — |
Reaction Steps
The title compound is prepared in a manner substantially analogous to Procedure A from 2-fluoro-4-hydroxybenzoic acid [CAS 65145-13-3] and (S)(+)-1-(2-pyrrolidinylmethyl)pyrrolidine. MS (ES+) m/e 293.1
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07846950B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-096aa8261a8449c787d33cc80d5c7ee5 |
| Source note | uspto-grants-2010_12 |