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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2261213Generated: October 29, 2026

3-(Chloromethyl)thiophene → HCID 11632760, compound

https://huagongshe.com/reaction/2261213

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)thiopheneHCID 12487462—
ReactantMethyl 2-fluoro-4-hydroxybenzoateHCID 22463192—
Reactant(R)-2-methyl-1-((S)-pyrrolidin-2-ylmethyl)pyrrolidineHCID 46911921—
ProductHCID 11632760HCID 11632760—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedures D and E using 2-fluoro-4-hydroxy-benzoic acid methyl ester [CAS 197507-22-5], 3-chloromethyl-thiophene [CAS 2746-23-8], and 2-(R)-Methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine. MS (ES+) m/e 403.3

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07846950B2
Source datasetuspto-grants-2010_12
ORD IDord-5f57652922ae43909d4ebaa7f540a645
Source noteuspto-grants-2010_12