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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2261214Generated: November 4, 2026

2-(Chloromethyl)thiophene → HCID 11682531, compound

https://huagongshe.com/reaction/2261214

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)thiopheneHCID 69830—
Reactant(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidineHCID 853152—
ReactantMethyl 2-fluoro-4-hydroxybenzoateHCID 22463192—
ProductHCID 11682531HCID 11682531—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedures D and E using 2-fluoro-4-hydroxy-benzoic acid methyl ester [CAS 197507-22-5], 2-chloromethyl-thiophene [CAS 765-50-4], and (S)(+)-1-(2-pyrrolidinylmethyl)pyrrolidine. MS (ES+) m/e 389.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07846950B2
Source datasetuspto-grants-2010_12
ORD IDord-72ed146cc652484aa155e7e09bc5e5c5
Source noteuspto-grants-2010_12