HCID 46197691, compound → HCID 25120344, compound

HRID 2261268Notes

Reaction equation

HRID 2261268 reaction equation
[CH:1]1([NH:4][C:5]([NH:7][C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[C:10](B3OC(C)(C)C(C)(C)O3)[CH:9]=2)=[O:6])[CH2:3][CH2:2]1.Br[C:25]1[C:30](=[O:31])[N:29]([CH3:32])[C:28]2[N:33]([C:36]3[C:41]([F:42])=[CH:40][CH:39]=[CH:38][C:37]=3[F:43])[N:34]=[CH:35][C:27]=2[CH:26]=1>>[CH:1]1([NH:4][C:5]([NH:7][C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[C:10]([C:25]3[C:30](=[O:31])[N:29]([CH3:32])[C:28]4[N:33]([C:36]5[C:41]([F:42])=[CH:40][CH:39]=[CH:38][C:37]=5[F:43])[N:34]=[CH:35][C:27]=4[CH:26]=3)[CH:9]=2)=[O:6])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 46197691HCID 46197691, compoundHCID 68738175HCID 68738175, compound

Product 1

HCID 25120344HCID 25120344, compound

Procedure

The title compound was prepared by a method similar to that described in Example 1, step 5 (Method A), starting from the 1-cyclopropyl-3-(4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea and 5-bromo-1-(2,6-difluorophenyl)-7-methyl-1H-pyrazolo[3,4-b]pyridin-6(7H)-one. MS (ESI, pos.ion) m/z: 317.2 (M+1).

Sources & evidence

ORD record
ord-8f83ff72101b4a998f5325ff929647db
Source dataset
uspto-grants-2010_12
Patent number
US07846944B2

Reaction notes

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