Carbon tetrabromide → HCID 57736291, compound

Participants

Reaction Steps

2.78 g of (5-pentafluoroethyl-isoxazol-3-yl)methanol was dissolved in 10 ml of diethyl ether, and 5.25 g of triphenylphosphine and 6.63 g of carbon tetrabromide were then added. The mixture was stirred at room temperature for 1 hour. The reaction mixture was subjected to silica gel column chromatography to obtain 1.83 g of 3-(bromomethyl)-5-pentafluoroethylisoxazole.

Provenance & Evidence