HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylmorpholine → HCID 178434651, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 4-Chlorobenzylamine | HCID 66036 | — |
| Reactant | HCID 178434647 | HCID 178434647 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178434651 | HCID 178434651 | 16.1% |
Reaction Steps
the title compound (21 mg) was prepared from crude 2-(5-amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonyl chloride (100 mg, 0.30 mmol), 4-chlorobenzylamine (74 μL, 0.60 mmol) and PS-NMM (0.320 g, 0.60 mmol) in 5 mL of methanol. MS (m/z, ES+): 434.4 (Cl35 M+1, 100%), 436.4 (Cl37 M+1, 40%). Yield=16%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07847101B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-15852cd02f7e4bd5b9f6d21250489f15 |
| Source note | uspto-grants-2010_12 |