HCID 57443248, compound → HCID 67528672, compound

HRID 2261733Notes

Reaction equation

HRID 2261733 reaction equation
[CH2:1]([O:3][C:4](=[O:15])[C:5](=[O:14])[C:6]([CH:11]1[CH2:13][CH2:12]1)=[CH:7][N:8]([CH3:10])[CH3:9])[CH3:2].[CH2:16](OC(=O)C(=O)CC1CCC1)C>>[CH2:1]([O:3][C:4](=[O:15])[C:5](=[O:14])[C:6]([CH:11]1[CH2:13][CH2:12][CH2:16]1)=[CH:7][N:8]([CH3:9])[CH3:10])[CH3:2]

Participants

3

Reactant 2

HCID 57443248HCID 57443248, compoundHCID 66906104HCID 66906104, compound

Product 1

HCID 67528672HCID 67528672, compoundYield 51%

Procedure

The title compound (0.663, 51%) is prepared essentially as described in the preparation of 3-cyclopropyl-4-dimethylamino-2-oxo-but-3-enoic acid ethyl ester using 3-cyclobutyl-2-oxo-propionic acid ethyl ester. LC-ES/MS m/e 226.0 (M+1)

Sources & evidence

ORD record
ord-ac8c4361b12044f89a2d23c7d1133384
Source dataset
uspto-grants-2010_12
Patent number
US07846960B2

Reaction notes

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