HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Methoxy-phenyl)-benzo[b]thiophene-6-carboxylic acid methyl ester → 2-(4-Hydroxy-phenyl)-benzo[b]thiophene-6-carboxylic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Methoxy-phenyl)-benzo[b]thiophene-6-carboxylic acid methyl ester | HCID 57443283 | — |
| Reactant | Ethyl 2-(4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate | HCID 135509402 | — |
| Product | 2-(4-Hydroxy-phenyl)-benzo[b]thiophene-6-carboxylic Acid Methyl Ester | HCID 17962524 | 12% |
Reaction Steps
The title compound (57 mg, 12%) is prepared essentially according to the preparation of 2-(4-Hydroxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester using 2-(4-methoxy-phenyl)-benzo[b]thiophene-6-carboxylic acid methyl ester. LC-ES/MS m/e 283 (M−1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07846960B2 |
| Source dataset | uspto-grants-2010_12 |
| ORD ID | ord-e571cf2f7e6844e380e617cff73a106d |
| Source note | uspto-grants-2010_12 |