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HRID2262089

反应详情

EQUATION

反应方程式

HRID 2262089 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)C1CCNC1
HCID3419356

3-(methylsulfonyl)pyrrolidine

C5H11NO2S

结构：O=C(O)c1cc2nc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)c2s1
HCID59593141

2-(1H-Indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidine-6-carboxylic acid

C18H15N5O3S

PRODUCTS

生成物

1
结构：CS(=O)(=O)C1CCN(C(=O)c2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)C1
HCID59593052

(2-(1H-indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)(3-(methylsulfonyl)pyrrolidin-1-yl)methanone

C23H24N6O4S2

PROCEDURE

实验过程

2-(1H-Indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidine-6-carboxylic acid 13 (45 mg) was coupled to 3-(methylsulfonyl)pyrrolidine via General Procedure B. The product was purified via reverse phase HPLC to give 26.1 mg of 168. MS (Q1) 513.1 (M)+.

WORKUP

后处理

  1. customThe product was purified via reverse phase HPLC