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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2262095Generated: November 2, 2026

3,3-Dimethylbutanoyl chloride → N-(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)-3,3-dimethylbutanamide

https://huagongshe.com/reaction/2262095

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,3-Dimethylbutanoyl chlorideHCID 81514—
Reactant2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-amineHCID 59592868—
ProductN-(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)-3,3-dimethylbutanamideHCID 86618392—

Reaction Steps

2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-amine (40 mg) was reacted with 41 μL of tert-butylacetyl chloride via General Procedure G to give N-(2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)-3,3-dimethylbutanamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07846929B2
Source datasetuspto-grants-2010_12
ORD IDord-74b611bcc24d498ba26c8ad4bf55f8a5
Source noteuspto-grants-2010_12